pre-clinical Archives - EyeResearchNow.com

March 11, 2023 Cornea

Engineering Corneal Endothelium Transplants Using SMILE Lenticules

These findings demonstrate that this techniques of using decellularized SMILE (refractive surgery) lenticules, accomplished with a chemical-free-method, is feasible and suitable for constructing the corneal endothelium for transplantation.

July 26, 2020 Ophthalmic Pathology

Fenofibrate may prevent ocular surface squamous metaplasia

Normally used to lower triglyceride levels in the blood, fenofibrate may have some potential as a preventative agent to prevent

July 12, 2020 Cornea

Hypoxia regulates meibomian gland function

Decreased oxygen in the local environment is shown to be essential for the normal function of meibomian glands.

April 15, 2020 Orbit

The effect of guggulsterone on primary orbital fibroblasts

This phytosterol was investigated as a possible candidate drug for Graves’ ophthalmopathy.

November 4, 2019 Iris and Ciliary Body

Eye rubbing linked to increase in intraocular pressure

Continuous monitoring of experimental macaques showed that this mindless habit can increase intraocular pressure, predisposing the individual to eye conditions

November 2, 2019 Cornea

Progenitor cells exist in the transitional zone between the peripheral corneal endothelium and trabecular meshwork

These cells are arranged in two layers, express stem markers, and may hold the key for increasing the regenerative capacity

September 16, 2019 Adnexa

Nerve stimulation as a treatment for dry eye disease

Topical medications can be of limited efficacy. Chronic nerve stimulation of the lacrimal gland can be a better treatment option.